Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users

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منابع مشابه

Psychomotor performance of long-term benzodiazepine users before, during, and after benzodiazepine discontinuation.

Long-term (mean, 8 years) users of benzodiazepines (BZs) were administered a small battery of cognitive tests on three occasions (before BZ taper, and 5 and 12 weeks post taper) as part of their BZ discontinuation program. Ninety-six patients had 5-week and 77 patients had 12-week data. For taper successes, BZ-free status was confirmed by weekly BZ plasma level determinations. Age and education...

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Cognitive behavioural therapy improved benzodiazepine discontinuation in chronic insomnia.

Baillargeon L, Landreville P, Verreault R, et al. Discontinuation of benzodiazepines among older insomniac adults treated with cognitive-behavioural therapy combined with gradual tapering: a randomized trial. CMAJ 2003;169:1015–20. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

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Cognitive behavioral therapy aided discontinuation of benzodiazepine in chronic insomnia.

P a t i e n t s 65 patients ≥ 50 years of age (mean age 67 y, 58% women) with chronic insomnia (> 6 mo) who had impaired daytime functioning or mood disturbances, had been taking a benzodiazepine nightly for ≥ 3 months, and were unable to refrain from taking a hypnotic for fear of poor sleep, or reported sleep efficiency (total sleep time/time in bed × 100) < 80% over a 2-week period. Exclusion...

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Facilitation of Benzodiazepine Discontinuation by Melatonin

Background: Benzodiazepines are the most frequently used drug for the treatment of insomnia. Prolonged use of benzodiazepine therapy is not recommended. However, many patients, particularly older patients, have difficulties discontinuing therapy. Melatonin, a hormone that is produced at night by the pineal gland, promotes normal sleep in humans and augments sleep induction by benzodiazepine the...

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The absence of benzodiazepine craving in a general practice benzodiazepine discontinuation trial.

This study aimed to assess benzodiazepine craving longitudinally and to describe its time course by means of the Benzodiazepine Craving Questionnaire (BCQ). Subjects were long-term benzodiazepine users participating in a two-part treatment intervention aimed to reduce long-term benzodiazepine use in general practice in The Netherlands. Four repeated measurements of benzodiazepine craving were t...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2018

ISSN: 1465-1858

DOI: 10.1002/14651858.cd011481.pub2